SPARC Program

All organs in the body are innervated by nerves, which carry information to and from organs and modulate their function. Methods and medical devices that modulate these nerve signals are a potentially powerful way to treat many diseases and conditions, such as hypertension, heart failure, gastrointestinal disorders, type 2 diabetes, inflammatory disorders, and more.

The Common Fund’s Stimulating Peripheral Activity to Relieve Conditions (SPARC) program aims to transform our understanding of these nerve-organ interactions and ultimately advance the neuromodulation field towards precise treatment of diseases and conditions for which conventional therapies fall short.

Who We Are

The Consortium is made up of multiple projects all targeting the same goal: to characterize how the autonomic nervous system controls organ function.

Our Research

On the SPARC Portal, we currently have multiple contributions. Click below to find out more.

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Annual Reports

We are pleased to share our first annual public report describing highlights and plans for the SPARC platform.


History of SPARC

Read about the progress of the SPARC Program. It was founded in 2015 through a Common Fund initiative by the National Institutes of Health, with the goal of accelerating the development of therapeutic devices that modulate electrical activity in nerves to improve major organ function.